HIV Reservoirs – Control or Cure Is an Urgency

Current HAART (highly active antiretroviral therapy) patterns of HIV infection requires lifelong medication. This implies a long-term adherence, toxicity and cost. Despite these shortcuts is to HIV “viral reservoirs” and each time the intake end revived the infection. New therapeutic approaches are needed to target this virus reservoirs and allow a one-day HIV drug-free remission. First, we need a better study of the mechanisms of HIV persistence and screen for new drugs able to reach, the virus does not participate in a latent state and anatomical reservoirs, where HAART is a good spread. Several breakthroughs have been achieved over the past two years, so that the hope for a “cure” is no longer a dirty word … We have a scientific community to support this research with the aim of finding a cure in the next ten years.

The most common desire for everyone and every country that is the spread of HIV, a cure for HIV-infected and a vaccine to prevent it from spreading. We naturally want the disease from the face of the planet very similar, with the Small Pox exterminate been achieved on a global scale today. Unfortunately, it is easier said than done in today’s global environment. But not lost all hope of recovery.

Universal Access to Anti-HIV Therapy

HIV therapy refers to a combination of antiretroviral drugs that block the viral replication in order to alleviate the symptoms of HIV and the progression of the disease. This treatment has become so successful that the researchers observed a dramatic decrease in morbidity and mortality in the country to have access. The success of anti-HIV therapy has also caused quite a stir in terms of universal access to it.

The World Health Organization, WHO, for short, in 2003 announced that they live antiretroviral drugs to three million people in low and middle income by the year 2005 provide. It was affectionately called the 3 by 5 target and provide the foundation for many was depth to the universal access to HIV therapy. This goal was achieved with the introduction of antiretroviral drugs for more than a million people, but it was not reached until 2007. In 2006, the WHO has another goal, set to implement the universal access to HIV treatment, including prevention, treatment and care until the year 2010. As the reports started coming in 2008, it was clear that this goal can not be achieved in 2010.

Adherence To HIV Antiretroviral Therapy

Antiretroviral therapy, or art, was a huge benefit for HIV patients. Because of the ART, has been less people from HIV to AIDS. Consequently, they live longer and healthier lives. The key, of course, is to remain with the regime and taking medications as scheduled, on time, as prescribed by a doctor. This is called the compliance of antiretroviral therapy, and is an important thing to consider, given the speed with which HIV to AIDS patients. Did she stay with him or not? This is the second largest predictor for the progression of HIV to AIDS as the CD4 count is better. Although the long-term progression to AIDS requires the support of nearly 100% of ART, current calculations of the average 70% compliance with the art, are not even know where it is located near to survive long term needs.

As already mentioned, is more than 95% of compliance necessary for the long-term viral suppression. To achieve this level of compliance with ART for HIV patients must take daily treatment regime and not delay or miss a dose of more than 3 times in a month. This level of liability is much greater than for other chronic diseases, and it is much harder to maintain. Patients should be careful to take their medication.

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